Title : Combination of protease inhibitors for the treatment of HIV-1-infected patients: a review of pharmacokinetics and clinical experience.

Pub. Date : 2001 Dec

PMID : 11878403






2 Functional Relationships(s)
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1 The favourable pharmacokinetics of PIs in combination are a result of interactions through cytochrome P450 3A4 (CYP3A4) isoenzymes and, possibly, the multi-drug transporting P-glycoprotein (P-gp). Monothiopyrophosphoric acid ATP binding cassette subfamily B member 1 Homo sapiens
2 The favourable pharmacokinetics of PIs in combination are a result of interactions through cytochrome P450 3A4 (CYP3A4) isoenzymes and, possibly, the multi-drug transporting P-glycoprotein (P-gp). Monothiopyrophosphoric acid ATP binding cassette subfamily B member 1 Homo sapiens