Title : Expression of NADP+-dependent 15-hydroxyprostaglandin dehydrogenase mRNA in monkey ocular tissues and characterization of its recombinant enzyme.

Pub. Date : 2002 Mar

PMID : 11872167






3 Functional Relationships(s)
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1 Here, we isolated the cDNAs for the monkey homologues of NAD+- and NADP+-dependent types of 15-hydroxy PG dehydrogenase (PGDH) from lung and eye, respectively, and investigated the distribution of their mRNAs in the monkey eye. NAD 15-hydroxyprostaglandin dehydrogenase Homo sapiens
2 Here, we isolated the cDNAs for the monkey homologues of NAD+- and NADP+-dependent types of 15-hydroxy PG dehydrogenase (PGDH) from lung and eye, respectively, and investigated the distribution of their mRNAs in the monkey eye. NAD 15-hydroxyprostaglandin dehydrogenase Homo sapiens
3 The cDNAs for the NAD+- and NADP+-dependent types of PGDH contained an open reading frame of 798 and 831 bp encoding 266 and 277 amino acid residues with calculated molecular masses of 28.9 and 30.5 kDa, respectively. NAD 15-hydroxyprostaglandin dehydrogenase Homo sapiens