Protein Name | 15-hydroxyprostaglandin dehydrogenase |
---|---|
Organism | Homo sapiens |
Gene ID | 3248 |
Gene Symbol | HPGD |
UniProt | P15428 (PGDH_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
145
Total Number of Articles : 191 |
Description |
15-hydroxyprostaglandin dehydrogenase |
Gene Summary |
This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
synonyms |
|
Properties | |