Title : Cytochrome P450 2C9-induced endothelial cell proliferation involves induction of mitogen-activated protein (MAP) kinase phosphatase-1, inhibition of the c-Jun N-terminal kinase, and up-regulation of cyclin D1.

Pub. Date : 2002 May 3

PMID : 11867622






1 Functional Relationships(s)
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1 Overexpression of CYP 2C9 significantly increased the expression of MKP-1, as did incubation with 11,12-EET. 11,12-epoxy-5,8,14-eicosatrienoic acid cytochrome P450 family 2 subfamily C member 9 Homo sapiens