Title : Abnormally spliced beta-globin mRNAs: a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay.

Pub. Date : 2002 Mar 1

PMID : 11861299






1 Functional Relationships(s)
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1 We generated beta-globin gene constructs with this mutation and an iron-responsive element in the 5" untranslated region, which allowed specific experimental activation and inactivation of translation and, hence, NMD of this transcript. Iron hemoglobin subunit beta Homo sapiens