Title : Protective effect of thiaton, an antispasmodic drug, against indomethacin-induced intestinal damage in rats.

Pub. Date : 2002 Jan

PMID : 11855677






2 Functional Relationships(s)
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1 Indomethacin caused intestinal damage, accompanied with increase in enterobacterial translocation as well as inducible nitric oxide synthase (iNOS) and myeloperoxidase (MPO) activities, and these changes were significantly prevented by supplementation with 16,16-dimethyl prostaglandin E2 (dmPGE2). Indomethacin nitric oxide synthase 2 Rattus norvegicus
2 Indomethacin caused intestinal damage, accompanied with increase in enterobacterial translocation as well as inducible nitric oxide synthase (iNOS) and myeloperoxidase (MPO) activities, and these changes were significantly prevented by supplementation with 16,16-dimethyl prostaglandin E2 (dmPGE2). Indomethacin nitric oxide synthase 2 Rattus norvegicus