Title : Regulation of cyclooxygenase-2 expression by phospholipase D in human amnion-derived WISH cells.

Pub. Date : 2002 Mar

PMID : 11854442






2 Functional Relationships(s)
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1 In addition, evidence that PLD was involved in the stimulation of COX-2 expression was provided by the observations that COX-2 expression was stimulated by the dioctanoyl phosphatidic acid (PA) and that the prevention of PA dephosphorylation by 1-propranolol potentiated COX-2 expression by IL-1 beta. Phosphatidic Acids glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
2 In addition, evidence that PLD was involved in the stimulation of COX-2 expression was provided by the observations that COX-2 expression was stimulated by the dioctanoyl phosphatidic acid (PA) and that the prevention of PA dephosphorylation by 1-propranolol potentiated COX-2 expression by IL-1 beta. Phosphatidic Acids glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens