Title : Oxidized low-density lipoprotein associates strongly with carboxy-terminal domain of tissue factor pathway inhibitor and reduces the catalytic activity of the protein.

Pub. Date : 2002 Jan

PMID : 11848461






1 Functional Relationships(s)
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1 In the present study, it was found, by means of agarose gel electrophoresis, that the pre-incubation of full-length rTFPI with heparin or the carboxy (C)-terminal part (peptide 240-265) of TFPI prevented the association with ox-LDL in a dose-dependent manner. Heparin tissue factor pathway inhibitor Homo sapiens