Pub. Date : 2002 Feb
PMID : 11847531
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Albendazole metabolism in patients with neurocysticercosis: antipyrine as a multifunctional marker drug of cytochrome P450. | Antipyrine | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 2 | The present study investigates the isoform(s) of cytochrome P450 (CYP) involved in the metabolism of albendazole sulfoxide (ASOX) to albendazole sulfone (ASON) in patients with neurocysticercosis using antipyrine as a multifunctional marker drug. | Antipyrine | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 3 | The present study investigates the isoform(s) of cytochrome P450 (CYP) involved in the metabolism of albendazole sulfoxide (ASOX) to albendazole sulfone (ASON) in patients with neurocysticercosis using antipyrine as a multifunctional marker drug. | Antipyrine | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 4 | Since the CL(T) of antipyrine is a general measure of CYP enzymes but with a slight to moderate weight toward CYP1A2, we suggest the involvement of this enzyme in ASOX to ASON metabolism in man. | Antipyrine | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |