Pub. Date : 2002 Jan 15
PMID : 11841781
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Reevaluation of the mechanism by which lobeline alters dopamine function reveals that its primary mechanism is inhibition of dopamine uptake and promotion of dopamine release from the storage vesicles within the presynaptic terminal, via an interaction with the tetrabenazine-binding site on the vesicular monoamine transporter (VMAT2). | Lobeline | solute carrier family 18 member A2 | Rattus norvegicus |
| 2 | The development of lobeline and lobeline analogs with targeted selectivity at VMAT2 represents a novel class of therapeutic agents having good potential as efficacious treatments for methamphetamine abuse. | Lobeline | solute carrier family 18 member A2 | Rattus norvegicus |
| 3 | The development of lobeline and lobeline analogs with targeted selectivity at VMAT2 represents a novel class of therapeutic agents having good potential as efficacious treatments for methamphetamine abuse. | Lobeline | solute carrier family 18 member A2 | Rattus norvegicus |