Title : Synthesis, stability, and conformation of the formamidopyrimidine G DNA lesion.

Pub. Date : 2002 Jan 4

PMID : 11822460






1 Functional Relationships(s)
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1 In agreement with the recent X-ray structure of hOGG1 in complex with 8-oxo-7,8-dihydroguanine-containing DNA, we can conclude that repair enzymes can contact both lesions only via the N(7)-H group, which is a hydrogen-bond acceptor in guanine. Guanine 8-oxoguanine DNA glycosylase Homo sapiens