Title : Adenoviral retrograde gene transfer in motoneurons is greatly enhanced by prior intramuscular inoculation with botulinum toxin.

Pub. Date : 2002 Jan 20

PMID : 11812279






1 Functional Relationships(s)
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1 We injected botulinum neurotoxin A (BoNT) into muscles of normal C57BL/6 mice and transgenic mice expressing the G93A mutation in the superoxide dismutase 1 gene (SOD1-G93A mutation, a model of amyotrophic lateral sclerosis) several days before inoculation with adenoviruses. Superoxides superoxide dismutase 1, soluble Mus musculus