Title : Evidence for the formation of an ester between thrombin and heparin cofactor.

Pub. Date : 1975 Oct 20

PMID : 1180962






2 Functional Relationships(s)
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1 The nature of the binding between thrombin and the inhibitor is studied by treatment of the complex with 6 M guanidinium chloride, hydroxylamine, and dilute alkali. Hydroxylamine coagulation factor II, thrombin Homo sapiens
2 Treatment of dodecylsulfate-denatured complex with hydroxylamine results in dissociation of the complex to yield free thrombin and heparin cofactor. Hydroxylamine coagulation factor II, thrombin Homo sapiens