Title : [The role of nitric oxide on the functional change of interleukin-1 beta and interleukin-6 induced rat pancreatic islets of Langerhans].

Pub. Date : 1999 Jul

PMID : 11798681






1 Functional Relationships(s)
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1 RESULTS: IL-1 beta induced a significant increase in nitrite production, a decrease of islet cell DNA and insulin content and reduction of cell activity (MTT, P < 0.001); these changes were blocked by L-NMMA (P < 0.001). omega-N-Methylarginine interleukin 1 beta Rattus norvegicus