Title : Immunohistochemical detection of hypochlorite-modified proteins in glomeruli of human membranous glomerulonephritis.

Pub. Date : 2002 Jan

PMID : 11796821






4 Functional Relationships(s)
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1 Although the nature of the in vivo oxidants has not been clearly identified, increasing evidence suggested the myeloperoxidase (MPO)-H(2)O(2)-halide system to be responsible for the damage observed in leukocyte-dependent glomerulonephritis. halide myeloperoxidase Homo sapiens
2 Although the nature of the in vivo oxidants has not been clearly identified, increasing evidence suggested the myeloperoxidase (MPO)-H(2)O(2)-halide system to be responsible for the damage observed in leukocyte-dependent glomerulonephritis. halide myeloperoxidase Homo sapiens
3 The observed colocalization of HOCl-modified proteins and MPO in podocytes and adjacent basement membranes strengthens the assumption that the MPO-H(2)O(2)-halide system contributes to glomerular dysfunction in patients with membranous glomerulonephritis. halide myeloperoxidase Homo sapiens
4 The observed colocalization of HOCl-modified proteins and MPO in podocytes and adjacent basement membranes strengthens the assumption that the MPO-H(2)O(2)-halide system contributes to glomerular dysfunction in patients with membranous glomerulonephritis. halide myeloperoxidase Homo sapiens