Title : Retinoic acids repress constitutive active receptor-mediated induction by 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene of the CYP2B10 gene in mouse primary hepatocytes.

Pub. Date : 2002 Feb

PMID : 11792692






2 Functional Relationships(s)
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1 The nuclear orphan receptor constitutive active receptor (CAR) can be activated to induce CYP2B genes by the potent phenobarbital-type inducer 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOP) in which the receptor forms a heterodimer with the retinoid X receptor (RXR) and binds to a conserved enhancer element NR1. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene glutamate receptor, ionotropic, NMDA1 (zeta 1) Mus musculus
2 The nuclear orphan receptor constitutive active receptor (CAR) can be activated to induce CYP2B genes by the potent phenobarbital-type inducer 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOP) in which the receptor forms a heterodimer with the retinoid X receptor (RXR) and binds to a conserved enhancer element NR1. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene glutamate receptor, ionotropic, NMDA1 (zeta 1) Mus musculus