Title : [Bcl-2 antisense oligodeoxyribonucleotide increases apoptosis of lung carcinoma cells induced by cisplatin].

Pub. Date : 2000 Dec

PMID : 11778475






3 Functional Relationships(s)
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1 [Bcl-2 antisense oligodeoxyribonucleotide increases apoptosis of lung carcinoma cells induced by cisplatin]. Cisplatin BCL2 apoptosis regulator Homo sapiens
2 OBJECTIVE: To study the effect of antisense oligodeoxyribonucleotide (ODN) to apoptotic suppress gene bcl-2 on apoptosis of lung carcinoma cells induced by cisplatin. Cisplatin BCL2 apoptosis regulator Homo sapiens
3 CONCLUSION: Antisense oligodeoxyribonucleotide to bcl-2 can inhibit significantly the expression of bcl-2 of lung cancer cells and increase apoptosis of cancer cells induced by cisplatin. Cisplatin BCL2 apoptosis regulator Homo sapiens