Title : HLA-DR1 (DRB1*0101) and DR4 (DRB1*0401) use the same anchor residues for binding an immunodominant peptide derived from human type II collagen.

Pub. Date : 2002 Jan 1

PMID : 11751969






1 Functional Relationships(s)
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Protein Name
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1 As predicted based on the crystal structures, the majority of the CII-peptide binding affinity for DR1 and DR4 is controlled by the Phe(263); however, unexpectedly the adjacent Lys(264) also contributed significantly to the binding affinity of the peptide. Lysine serpin family D member 1 Homo sapiens