Title : An alternative explanation for the catalytic proficiency of orotidine 5'-phosphate decarboxylase.

Pub. Date : 2001 Dec 26

PMID : 11749542






1 Functional Relationships(s)
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1 Orotidine 5"-phosphate decarboxylase (ODCase) is the most proficient enzyme known, enhancing the rate of decarboxylation of orotidine 5"-phosphate (OMP) by a factor of 10(17), which corresponds to a DeltaDeltaG++ of approximately 24 kcal/mol. orotidylic acid uridine monophosphate synthetase Homo sapiens