Title : EGF and beta1 integrin convergently regulate migration of A431 carcinoma cell through MAP kinase activation.

Pub. Date : 2002 Jan 1

PMID : 11740868






2 Functional Relationships(s)
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1 Using a MAPK cascade inhibitor, PD98059, it was shown that EGF-induced migration on collagen was mediated by MAPK whereas EGF-induced migration on fibronectin and vitronectin was not. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one epidermal growth factor Homo sapiens
2 PD98059 also showed that activation of MAPK induced by EGF enhanced the adhesiveness of A431 cells to collagen. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one epidermal growth factor Homo sapiens