Title : [Proapoptotic effect of propofol on T cells].

Pub. Date : 2001 Oct

PMID : 11740418






2 Functional Relationships(s)
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1 RESULTS: Treated lymphocytes exhibit a significantly enhanced expression of Fas/FssL system associated with a decrease of Bcl2 expression at both 5 and 50 mg/ml propofol concentrations (p<0.05). Propofol BCL2 apoptosis regulator Homo sapiens
2 CONCLUSIONS: Propofol impairs, in vitro, both Fas/FasL and Bcl2 expressions on lymphocytes at clinically relevant concentrations but fails to induce apoptotic cell death. Propofol BCL2 apoptosis regulator Homo sapiens