Pub. Date : 2001 Dec
PMID : 11714865
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos. | Chlorpyrifos | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | Testosterone and the insecticide chlorpyrifos were used to assess the catalytic activities of the most common CYP3A4 allele (CYP3A4*1) and its allelic variants. | Chlorpyrifos | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 3 | CYP3A4 F189S exhibited lower turnover numbers for testosterone and chlorpyrifos, while CYP3A4 L293P had higher turnover numbers for both substrates. | Chlorpyrifos | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |