Title : Analysis of selective regions in the active sites of human cytochromes P450, 2C8, 2C9, 2C18, and 2C19 homology models using GRID/CPCA.

Pub. Date : 2001 Nov 22

PMID : 11708911






1 Functional Relationships(s)
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1 The selectivity analysis singled out CYP2C8 as the most different of the four CYP2C enzymes with amino acids with distinct properties in positions 114, 205, and 476 (Ser, Phe, and Ile, respectively) compared to the other enzymes. Serine cytochrome P450 family 2 subfamily C member 9 Homo sapiens