Pub. Date : 2001 Nov
PMID : 11699047
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Interestingly, GLUT-1 protein content was increased in adipose tissue ( thick approximate 150%) and skeletal muscle (approximately 50%) of obese rats and treatment with rosiglitazone increased it even more by 5.5-fold in fat and by 2.5-fold in muscle. | Rosiglitazone | solute carrier family 2 member 1 | Rattus norvegicus |
| 2 | Consistent with these results, basal (GLUT-1-mediated) transport rate of 3-O-methyl-D-glucose into isolated epitrochlearis muscle was elevated in response to rosiglitazone. | Rosiglitazone | solute carrier family 2 member 1 | Rattus norvegicus |
| 3 | In conclusion, rosiglitazone may improve insulin resistance in vivo by normalizing GLUT-4 protein content in adipose tissue and increasing GLUT-1 in skeletal muscle and fat. | Rosiglitazone | solute carrier family 2 member 1 | Rattus norvegicus |