Protein Name solute carrier family 2 member 1
Organism Rattus norvegicus
Gene ID 24778
Gene Symbol

Slc2a1

UniProt P11167 (GTR1_RAT)
Relationships Total Number of functionally related compound(s) : 247
Total Number of Articles : 438
Description

solute carrier family 2 member 1

Gene Summary

Enables several functions, including D-glucose transmembrane transporter activity; dehydroascorbic acid transmembrane transporter activity; and kinase binding activity. Involved in several processes, including cellular hyperosmotic response; cellular response to mechanical stimulus; and dehydroascorbic acid transport. Located in several cellular components, including Z disc; basolateral plasma membrane; and intercalated disc. Colocalizes with sarcolemma. Biomarker of hypertension; hypothyroidism; and middle cerebral artery infarction. Human ortholog(s) of this gene implicated in brain disease (multiple); carbohydrate metabolic disorder; myelomeningocele; obesity; and type 2 diabetes mellitus. Orthologous to human SLC2A1 (solute carrier family 2 member 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • solute carrier family 2, facilitated glucose transporter member 1
  • GLUT-1
  • Solute carrier family 2 a 1 (facilitated glucose transporter) brain
Click to show/hide the synonyms
Properties