Title : Upregulation of phosphodiesterase 1A1 expression is associated with the development of nitrate tolerance.

Pub. Date : 2001 Nov 6

PMID : 11696475






1 Functional Relationships(s)
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1 In cultured rat aortic VSMCs, angiotensin II (Ang II) increased PDE1A1 activity, and vinpocetine blocked the effect of Ang II on decrease in cGMP accumulation. Cyclic GMP angiotensinogen Rattus norvegicus