Title : [Changes in ulcerogenic response to non-steroidal anti-inflammatory drugs (NSAIDs) in adjuvant arthritic rats].

Pub. Date : 2001 Oct

PMID : 11676176






3 Functional Relationships(s)
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1 In addition, we recently found that cyclooxygenase-2 (COX-2) selective inhibitors, such as rofecoxib or celecoxib, induced apparent gastric lesions in arthritic rats, suggesting that a caution should be paid on the use of COX-2 selective inhibitors in RA patients. Celecoxib prostaglandin-endoperoxide synthase 2 Rattus norvegicus
2 In addition, we recently found that cyclooxygenase-2 (COX-2) selective inhibitors, such as rofecoxib or celecoxib, induced apparent gastric lesions in arthritic rats, suggesting that a caution should be paid on the use of COX-2 selective inhibitors in RA patients. Celecoxib prostaglandin-endoperoxide synthase 2 Rattus norvegicus
3 In addition, we recently found that cyclooxygenase-2 (COX-2) selective inhibitors, such as rofecoxib or celecoxib, induced apparent gastric lesions in arthritic rats, suggesting that a caution should be paid on the use of COX-2 selective inhibitors in RA patients. Celecoxib prostaglandin-endoperoxide synthase 2 Rattus norvegicus