Pub. Date : 1999 Apr 19
PMID : 11670948
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Difluoromethylcobalamin (CF(2)Cbl), a vitamin B(12) analogue with CHF(2) replacing CN, can be synthesized in a two-step procedure from aquocobalamin and CHClF(2). | Niacinamide | Cbl proto-oncogene | Homo sapiens |
| 2 | The packing motif of CF(2)Cbl is very similar to that described for wet vitamin B(12), a distorted hexagonal close packing of the cobalamin, with channels of water running parallel to the crystallographic c axis through the crystal at x = (1)/(4), y = 0, and x = (3)/(4), y = (1)/(2), respectively. | Niacinamide | Cbl proto-oncogene | Homo sapiens |
| 3 | A superposition of the crystal structures of vitamin B(12) and CF(2)Cbl shows a significant change at the molecular level. | Niacinamide | Cbl proto-oncogene | Homo sapiens |