Title : Tyrosine residues in phospholipase Cgamma 2 essential for the enzyme function in B-cell signaling.

Pub. Date : 2001 Dec 21

PMID : 11606584






1 Functional Relationships(s)
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1 The importance of growth factor-stimulated phosphorylation of specific tyrosine residues has been documented for PLCgamma1; however, despite the critical importance of PLCgamma2 in B-cell signal transduction, neither the tyrosine kinase(s) that directly phosphorylate PLCgamma2 nor the sites in PLCgamma2 that become phosphorylated after stimulation are known. Tyrosine phospholipase C gamma 1 Homo sapiens