Title : Losartan inhibits the angiotensin II-induced modifications on fibrinolysis and matrix deposition by primary human vascular smooth muscle cells.

Pub. Date : 2001 Nov

PMID : 11602818






1 Functional Relationships(s)
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1 Ang II (1 microM ) enhanced DNA synthesis and secretion of PAI-1 and glycosaminoglycans and decreased secretion of MMP-2 activity and tPA, whereas it had no effect on secretion of TIMPs and glycosaminoglycans associated with cell layers. Glycosaminoglycans angiotensinogen Homo sapiens