Title : Gemfibrozil is a potent inhibitor of human cytochrome P450 2C9.

Pub. Date : 2001 Nov

PMID : 11602509






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In addition, gemfibrozil exhibited somewhat smaller inhibitory effects on CYP2C19 and CYP1A2 activities, with K(i) (IC(50)) values of 24 (47) microM and 82 (136) microM, respectively. Gemfibrozil cytochrome P450 family 2 subfamily C member 19 Homo sapiens
2 Gemfibrozil may also impair clearance of CYP2C19 and CYP1A2 substrates, but inhibition of other CYP isoforms is unlikely. Gemfibrozil cytochrome P450 family 2 subfamily C member 19 Homo sapiens