Title : Intragastric DMXB-A, an alpha7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice.

Pub. Date : 2001 Oct 1

PMID : 11600102






2 Functional Relationships(s)
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1 METHODS: Our study examined the inhibition of the P20-N40 auditory evoked potential in DBA/2 mice after intragastric administration of DMXB-A (3-2,4-dimethoxybenzylidine anabaseine), an alpha7 nicotinic receptor partial agonist. 3-(2,4-dimethoxybenzylidene)anabaseine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 This improvement was blocked by alpha-bungarotoxin, but not mecamylamine, indicating that DMXB-A exerts its effects through the alpha7 nicotinic receptor. 3-(2,4-dimethoxybenzylidene)anabaseine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus