Title : The evolution of acetyl-CoA synthase.

Pub. Date : 2001 Aug-Oct

PMID : 11599178






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Class I ACS"s catalyze the synthesis of acetyl-CoA from CO2 + 2e-, CoA, and a methyl group, and contain 5 types of subunits (alpha, beta, gamma, delta, and epsilon). N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide acyl-CoA synthetase short chain family member 2 Homo sapiens
2 Class III ACS"s catalyze the same reaction as Class I enzymes, but use pyruvate as a source of CO2 and 2e-, and are composed of 2 autonomous proteins, an alpha 2 beta 2 tetramer and a gamma delta heterodimer. N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)-4-((4-fluorobenzyl)oxy)pyridine-2,6-dicarboxamide acyl-CoA synthetase short chain family member 2 Homo sapiens