Protein Name acyl-CoA synthetase short chain family member 2
Organism Homo sapiens
Gene ID 55902
Gene Symbol

ACSS2

UniProt Q9NR19 (ACSA_HUMAN), Q6DKJ3 (Q6DKJ3_HUMAN), Q96FY7 (Q96FY7_HUMAN), Q4G0E8 (Q4G0E8_HUMAN)
Relationships Total Number of functionally related compound(s) : 141
Total Number of Articles : 117
Description

acyl-CoA synthetase short chain family member 2

Gene Summary

This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

synonyms
  • acetyl-coenzyme A synthetase, cytoplasmic
  • acetate thiokinase
  • acetate-CoA ligase
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Properties