Title : Protection against chemotherapy-induced cytotoxicity by cyclin-dependent kinase inhibitors (CKI) in CKI-responsive cells compared with CKI-unresponsive cells.

Pub. Date : 2001 Sep 27

PMID : 11593424






1 Functional Relationships(s)
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1 Induction of p16(Ink4a), p21(Waf1), or p27(Kip1) conferred strong resistance to paclitaxel- or cisplatin-mediated cytotoxicity on the CKI-responsive A431 cells but not on the CKI-unresponsive SiHa cells. Cisplatin cyclin dependent kinase inhibitor 1B Homo sapiens