Title : Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization.

Pub. Date : 2001 Oct 2

PMID : 11591323






2 Functional Relationships(s)
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1 We show that serum and the serum lipid, lysophosphatidic acid (LPA), increased Cdc42 GTP levels and triggered MTOC reorientation in serum-starved wounded monolayers of 3T3 fibroblasts. lysophosphatidic acid cell division cycle 42 Homo sapiens
2 Cdc42, but not Rho or Rac, was both sufficient and necessary for LPA-stimulated MTOC reorientation. lysophosphatidic acid cell division cycle 42 Homo sapiens