Title : Zap-70-independent Ca(2+) mobilization and Erk activation in Jurkat T cells in response to T-cell antigen receptor ligation.

Pub. Date : 2001 Nov

PMID : 11585897






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CD3 stimulation of P116 cells also induced tyrosine phosphorylation of phospholipase C-gamma1 (PLCgamma1) and increased the intracellular Ca(2+) concentration. Tyrosine phospholipase C gamma 1 Homo sapiens
2 CD3 stimulation of P116 cells also induced tyrosine phosphorylation of phospholipase C-gamma1 (PLCgamma1) and increased the intracellular Ca(2+) concentration. Tyrosine phospholipase C gamma 1 Homo sapiens
3 The physiologic relevance of these signaling events is further supported by the finding of PLCgamma1 tyrosine phosphorylation, Erk activation, and CD69 upregulation in P116 cells on stimulation with superantigen and antigen-presenting cells. Tyrosine phospholipase C gamma 1 Homo sapiens