Title : Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells.

Pub. Date : 2001 Oct 1

PMID : 11585739






1 Functional Relationships(s)
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1 Dose-dependent reduction in EGF-stimulated A549 motility was observed with the PD98059 MEK1 inhibitor and the batimastat (BB-94) inhibitor of MMP activity, but not with the SB203580 inhibitor of p38 kinase. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one epidermal growth factor Homo sapiens