Pub. Date : 2001 Oct 9
PMID : 11580286
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effects of ticlopidine on CYP 2C19 are very analogous with those previously described for the inactivation of CYP 2C9 by tienilic acid. | Ticlopidine | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 2 | This suggests that a similar electrophilic intermediate, possibly a thiophene S-oxide, is involved in the inactivation of CYP 2C19 and CYP 2C9 by ticlopidine and tienilic acid, respectively. | Ticlopidine | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |