Title : COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk.

Pub. Date : 2001 Oct

PMID : 11577006






7 Functional Relationships(s)
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Protein Name
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1 COMT(HH) (high activity COMT homozygote) breast cancer cases had statistically significantly lower levels of homocysteine (P = 0.05) and cysteine (P = 0.04) and higher levels of PLP (P = 0.02) than COMT(HH) controls. Homocysteine catechol-O-methyltransferase Homo sapiens
2 COMT(HH) (high activity COMT homozygote) breast cancer cases had statistically significantly lower levels of homocysteine (P = 0.05) and cysteine (P = 0.04) and higher levels of PLP (P = 0.02) than COMT(HH) controls. Homocysteine catechol-O-methyltransferase Homo sapiens
3 COMT(HH) (high activity COMT homozygote) breast cancer cases had statistically significantly lower levels of homocysteine (P = 0.05) and cysteine (P = 0.04) and higher levels of PLP (P = 0.02) than COMT(HH) controls. Homocysteine catechol-O-methyltransferase Homo sapiens
4 In contrast, COMT(LL) (low activity COMT homozygote) cases had higher levels of homocysteine than COMT(LL) controls (P = 0.05). Homocysteine catechol-O-methyltransferase Homo sapiens
5 In contrast, COMT(LL) (low activity COMT homozygote) cases had higher levels of homocysteine than COMT(LL) controls (P = 0.05). Homocysteine catechol-O-methyltransferase Homo sapiens
6 In contrast, COMT(LL) (low activity COMT homozygote) cases had higher levels of homocysteine than COMT(LL) controls (P = 0.05). Homocysteine catechol-O-methyltransferase Homo sapiens
7 An increasing number of COMT(L) alleles was significantly associated with increased breast cancer risk in women with below median levels of folate (P(trend) = 0.05) or above median levels of homocysteine (P(trend) = 0.02). Homocysteine catechol-O-methyltransferase Homo sapiens