Title : Membrane raft-dependent regulation of phospholipase Cgamma-1 activation in T lymphocytes.

Pub. Date : 2001 Oct

PMID : 11564877






2 Functional Relationships(s)
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Protein Name
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1 Raft-targeted PLCgamma1 was constitutively tyrosine phosphorylated and induced constitutive NF-AT-dependent transcription and interleukin-2 secretion in Jurkat cells. Tyrosine phospholipase C gamma 1 Homo sapiens
2 Tyrosine phosphorylation of raft-targeted PLCgamma1 did not require Zap-70 or the interaction with the adapters Lat and Slp-76, molecules that are necessary for TCR signaling. Tyrosine phospholipase C gamma 1 Homo sapiens