Title : Lipopolysaccharide-induced increase of prostaglandin E(2) is mediated by inducible nitric oxide synthase activation of the constitutive cyclooxygenase and induction of membrane-associated prostaglandin E synthase.

Pub. Date : 2001 Oct 1

PMID : 11564815






1 Functional Relationships(s)
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1 The LPS-induced increase in PGE(2) concentration was mediated by NOS2-derived NO-dependent activation of COX-1 pathway and by induction of mPGES. Dinoprostone nitric oxide synthase 2 Rattus norvegicus