Title : Abnormalities of Gq-mediated cell signaling in Bartter and Gitelman syndromes.

Pub. Date : 2001 Sep

PMID : 11532083






3 Functional Relationships(s)
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Protein Name
Organism
1 In BS/GS, PKC stimulation with PMA dose dependently reduced ecNOS gene expression (from 0.80 +/- 0.05 to 0.78 +/- 0.03 densitometric units; PMA 50 nmol/L, P = NS; to 0.55 +/- 0.07, PMA 100 nmol/L, P < 0.001) to an undetectable expression (PMA 200 nmol/L). Tetradecanoylphorbol Acetate nitric oxide synthase 3 Homo sapiens
2 In BS/GS, PKC stimulation with PMA dose dependently reduced ecNOS gene expression (from 0.80 +/- 0.05 to 0.78 +/- 0.03 densitometric units; PMA 50 nmol/L, P = NS; to 0.55 +/- 0.07, PMA 100 nmol/L, P < 0.001) to an undetectable expression (PMA 200 nmol/L). Tetradecanoylphorbol Acetate nitric oxide synthase 3 Homo sapiens
3 In BS/GS, PKC stimulation with PMA dose dependently reduced ecNOS gene expression (from 0.80 +/- 0.05 to 0.78 +/- 0.03 densitometric units; PMA 50 nmol/L, P = NS; to 0.55 +/- 0.07, PMA 100 nmol/L, P < 0.001) to an undetectable expression (PMA 200 nmol/L). Tetradecanoylphorbol Acetate nitric oxide synthase 3 Homo sapiens