Pub. Date : 2001 Sep
PMID : 11530878
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | One critical aspect of intracellular signaling is regulation of key cell functions by lipid mediators, in particular the generation of a key mediator, phosphatidic acid (PA) via the hydrolysis of phosphatidylcholine by phospholipase D (PLD). | Phosphatidic Acids | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 2 | One critical aspect of intracellular signaling is regulation of key cell functions by lipid mediators, in particular the generation of a key mediator, phosphatidic acid (PA) via the hydrolysis of phosphatidylcholine by phospholipase D (PLD). | Phosphatidic Acids | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 3 | One critical aspect of intracellular signaling is regulation of key cell functions by lipid mediators, in particular the generation of a key mediator, phosphatidic acid (PA) via the hydrolysis of phosphatidylcholine by phospholipase D (PLD). | Phosphatidic Acids | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 4 | One critical aspect of intracellular signaling is regulation of key cell functions by lipid mediators, in particular the generation of a key mediator, phosphatidic acid (PA) via the hydrolysis of phosphatidylcholine by phospholipase D (PLD). | Phosphatidic Acids | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 5 | Research in this field has intensified, due in part to the recent cloning and partial characterization of the two PLD isoforms in mammalian cells, and this work has contributed significantly to our understanding of events downstream of PA generation. | Phosphatidic Acids | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 6 | This review summarises the data implicating signaling via PLD in these cell functions, obtained from: (i) molecular analyses of PLD/effector interactions, (ii) correlation between PA production and cell responses, (iii) experimental manipulation of PA levels, (iv) inhibition of PLD regulators, and (v) direct inhibition of PA production. | Phosphatidic Acids | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 7 | This review summarises the data implicating signaling via PLD in these cell functions, obtained from: (i) molecular analyses of PLD/effector interactions, (ii) correlation between PA production and cell responses, (iii) experimental manipulation of PA levels, (iv) inhibition of PLD regulators, and (v) direct inhibition of PA production. | Phosphatidic Acids | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 8 | This review summarises the data implicating signaling via PLD in these cell functions, obtained from: (i) molecular analyses of PLD/effector interactions, (ii) correlation between PA production and cell responses, (iii) experimental manipulation of PA levels, (iv) inhibition of PLD regulators, and (v) direct inhibition of PA production. | Phosphatidic Acids | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |