Title : 3D model for TM region of the AT-1 receptor in complex with angiotensin II independently validated by site-directed mutagenesis data.

Pub. Date : 2001 Sep 7

PMID : 11527428






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Indeed, the model brings in contact the residues of AII responsible for agonistic activity, Tyr(4), His(6), and Phe(8), with many residues of AT-1 involved in signal transduction according to site-directed mutagenesis. Histidine angiotensinogen Homo sapiens