Pub. Date : 2001 Sep 1
PMID : 11516159
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The role of cytosolic and mitochondrial serine hydroxymethyltransferase in supplying one-carbon groups for purine and thymidylate biosynthesis in MCF-7 cells was investigated by observing folate-mediated one-carbon metabolism of l-[3-(13)C]serine, [2-(13)C]glycine, and [(13)C]formate. | Glycine | serine hydroxymethyltransferase 1 | Homo sapiens |
2 | The cleavage of serine to glycine and 5,10-methylenetetrahydrofolate by cytosolic serine hydroxymethyltransferase does not appear to be a major source of one-carbon groups for either purine or thymidylate biosynthesis. | Glycine | serine hydroxymethyltransferase 1 | Homo sapiens |