Title : Effects of spectator ligands on the specific recognition of intrastrand platinum-DNA cross-links by high mobility group box and TATA-binding proteins.

Pub. Date : 2001 Oct 19

PMID : 11514569






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Electrophoretic mobility shift assays show that both the A and B domains of HMGB1 as well as TBP discriminate between different platinum-DNA adducts. Platinum high mobility group box 1 Homo sapiens
2 HMGB1 domain A is the most sensitive to the nature of the spectator ligands on platinum. Platinum high mobility group box 1 Homo sapiens