Title : Nontoxic doses of suramin enhance activity of paclitaxel against lung metastases.

Pub. Date : 2001 Aug 15

PMID : 11507065






1 Functional Relationships(s)
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1 We recently reported that acidic (aFGF) and basic (bFGF) fibroblast growth factors confer a broad spectrum chemoresistance in solid tumors, and that suramin, an inhibitor of multiple growth factors including aFGF and bFGF, enhanced the in vitro antitumor activity of several anticancer drugs including paclitaxel (Song, S., et al., Proc. Suramin fibroblast growth factor 1 Homo sapiens