Title : Contributions of five human cytochrome P450 isoforms to the N-demethylation of clozapine in vitro at low and high concentrations.

Pub. Date : 2001 Aug

PMID : 11504269






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Thus, the present in vitro study on clozapine N-demethylation suggests that CYP1A2 is the most important form at low concentrations, which is in agreement with clinical findings. Nitrogen cytochrome P450 family 1 subfamily A member 2 Homo sapiens