Title : The green tea polyphenol (-)-epigallocatechin-3-gallate blocks nuclear factor-kappa B activation by inhibiting I kappa B kinase activity in the intestinal epithelial cell line IEC-6.

Pub. Date : 2001 Sep

PMID : 11502884






2 Functional Relationships(s)
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1 We previously showed that green tea polyphenols inhibited endotoxin-mediated tumor necrosis factor-alpha (TNF alpha) production by blocking NF-kappa B activation. Polyphenols tumor necrosis factor Rattus norvegicus
2 IEC-6 cells pretreated with an extract of green tea polyphenols (GrTPs; 0--0.4 mg/ml) had diminished TNF alpha-induced IKK and NF-kappa B activity. Polyphenols tumor necrosis factor Rattus norvegicus